Recommended positive controls: 293T, A431.
Predicted reactivity: Mouse (90%), Rat (90%), Bovine (91%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a core intraflagellar transport (IFT) protein which belongs to a multi-protein complex involved in the transport of ciliary proteins along axonemal microtubules. IFT proteins are found at the base of the cilium as well as inside the cilium, where they assemble into long arrays between the ciliary base and tip. This protein, together with intraflagellar transport protein 81, binds and transports tubulin within cilia and is required for ciliogenesis. Naturally occurring mutations in this gene are associated with amyotrophic lateral sclerosis--frontotemporal dementia and Bardet-Biedl Syndrome.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
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Protein Aliases: Capillary morphogenesis gene 1 protein; capillary morphogenesis protein 1; CMG-1; coiled-coil domain containing 2; Coiled-coil domain-containing protein 2; intraflagellar transport 74 homolog; Intraflagellar transport protein 74 homolog
Gene Aliases: CCDC2; CMG-1; CMG1; IFT74
UniProt ID: (Human) Q96LB3
Entrez Gene ID: (Human) 80173