Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Sequence homology: Cow: 100%; Dog: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%
Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is required for the association of CNOT10 with the CCR4-NOT complex. Seems not to be required for complex deadenylase function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CCR4-NOT transcription complex subunit 11; CCR4-NOT transcription complex, subunit 11; UPF0760 protein C2orf29
Gene Aliases: C2orf29; C40; CNOT11
UniProt ID: (Human) Q9UKZ1
Entrez Gene ID: (Human) 55571
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