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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Chicken / IgY|
|Immunogen||Synthetic peptide based on the human CNTF protein.|
|Contains||0.02% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|ELISA (ELISA)||1:500 - 1:2000|
|Immunohistochemistry (IHC)||1:50 - 1:500|
|Western Blot (WB)||1:500 - 1:2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-9521 detects CNTF in human, mouse and rat samples.
PA1-9521 has been successfully used in Western blot, ELISA,and immunohistochemistry procedures. By Western blot, PA1-9521 detects a 23 kDa protein representing CNTF.
PA1-9521 immunogen is a synthetic peptide based on the human CNTF protein.
Store at 4°C for up to 1 week, and -20°C as undiluted liquid long-term.
The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of ZFP91 and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Ciliary neurotrophic factor; ciliary neurotropic factor; CNTF
AI429687; CNTF; HCNTF