This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: RSSQALAFES SAGIFMGNAG ATGLERFTGS LQQLTVHPDP RTPEELCDPE ESSASGETSG LQEADGVAEI LEAVTYTQAS PKEAKVEPIN TPPTPSSPFE DMELSGEPVP E
Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 77%.
This gene encodes the alpha chain of type XV collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Type XV collagen has a wide tissue distribution but the strongest expression is localized to basement membrane zones so it may function to adhere basement membranes to underlying connective tissue stroma. The proteolytically produced C-terminal fragment of type XV collagen is restin, a potentially antiangiogenic protein that is closely related to endostatin. Mouse studies have shown that collagen XV deficiency is associated with muscle and microvessel deterioration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: COFA1; Collagen alpha-1(XV) chain; collagen type XV proteoglycan; collagen XV, alpha-1 polypeptide; collagen, type XV, alpha 1; Endostatin-XV; Related to endostatin; Restin; Restin-2; Restin-3; Restin-4; Restin-I; Restin-II; Restin-III; Restin-IV
Gene Aliases: COL15A1
UniProt ID: (Human) P39059
Entrez Gene ID: (Human) 1306