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Product Details
PA5-59975
| Applications | Tested Dilution | Publications |
|---|---|---|
Immunohistochemistry (IHC) |
1:200-1:500 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant protein corresponding to Human COL19A1 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.2 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.2, with 40% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2640015 |
Product Specific Information
Immunogen sequence: VTVRDKTEES CPILRIEGHQ LTYDNINKLE VSGFDLGDSF SLRRAFCESD KTCFKLGSAL LIRDTIKIFP KGLPEEYSVA AMFRVRRNAK KERWFLWQVL
Highest antigen sequence identity to the following orthologs: Mouse - 72%, Rat - 70%.
Target Information
Collagen Type XIX is an 1,142 amino acid protein encoded by the human gene COL19A1. Collagen Type XIX belongs to the fibril-associated collagens with interrupted helices (FACIT) family. Collagen Type XIX is thought to act as a cross-bridge between collagen fibrils and other extracellular matrix molecules. Collagen Type XIX is also believed to be involved in skeletal myogenesis in the developing esophagus. It may also play a role in organization of the pericellular matrix or the sphinteric smooth muscle. Collagen Type XIX is normally found as an oligomer, the subunits being disulfide-linked. Expression of Collagen Type XIX is mainly localized to vascular, neuronal, mesenchymal, and some epithelial basement membrane zones in umbilical cord.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: a1 chain of type XIX collagen; collagen alpha 1 (Y) chain; Collagen alpha-1(XIX) chain; Collagen alpha-1(Y) chain; collagen XIX, alpha-1 polypeptide; collagen, type XIX, alpha 1
Gene Aliases: COL19A1; COL9A1L; D6S228E
UniProt ID: (Human) Q14993
Entrez Gene ID: (Human) 1310
Molecular Function:
extracellular matrix structural protein
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