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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:1,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:50-1:500 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
COMMD3 Fusion Protein Ag23968 (18-195 aa encoded by BC022898) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.37 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.1% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: RSFDSNAFT LLLRAAFQSL LDAQADEAVL DHPDLKHIDP VVLKHCHAAA ATYILEAGKH RADKSTLSTY LEDCKFDRER IELFCTEYQN NKNSLEILLG SIGRSLPHIT DVSWRLEYQI KTNQLHRMYR PAYLVTLSVQ NTDSPSYPEI SFSCSMEQLQ DLVGKLKDAS KSLERATQL (18-195 aa encoded by BC022898)
COMMD3 may modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. may down-regulate activation of NF-kappa-B. Modulates Na(+) transport in epithelial cells by regulation of apical cell surface expression of amiloride-sensitive sodium channel (ENaC) subunits.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Bmi-1 upstream gene protein; Bmi1 upstream; Bup protein; COMM domain-containing protein 3; Protein Bup; Protein PIL
Gene Aliases: AW550818; BUP; C10orf8; COMMD3; D2Ertd542e
UniProt ID: (Human) Q9UBI1, (Mouse) Q63829
Entrez Gene ID: (Human) 23412, (Mouse) 12238
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