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May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). May down-regulate activation of NF-kappa-B (PubMed:15799966). Modulates Na(+) transport in epithelial cells by regulation of apical cell surface expression of amiloride-sensitive sodium channel (ENaC) subunits (PubMed:23637203).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: COMM domain-containing protein 9; neuroprotective protein 9
Gene Aliases: 1810029F08Rik; AA409293; COMMD9; HSPC166
UniProt ID: (Human) Q9P000, (Mouse) Q8K2Q0
Entrez Gene ID: (Human) 29099, (Rat) 295956, (Mouse) 76501
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