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Product Details
BS-9123R
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:100-1:500 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Mouse, Rat, Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
KLH conjugated synthetic peptide derived from human COPS4. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Protein A |
Storage buffer |
PBS with 50% glycerol, 1% BSA |
Contains |
0.09% sodium azide |
Storage conditions |
-20°C |
Target Information
This gene encodes one of eight subunits composing COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: COP9 (constitutive photomorphogenic) homolog, subunit 4; COP9 (constitutive photomorphogenic), subunit 4; COP9 complex S4; COP9 constitutive photomorphogenic homolog subunit 4; COP9 constitutive photomorphogenic-like protein subunit 4; COP9 signalosome complex subunit 4; JAB1-containing signalosome subunit 4; SGN4; signalosome subunit 4; testis tissue sperm-binding protein Li 42a
Gene Aliases: AW208976; COPS4; CSN4; D5Ertd774e
UniProt ID: (Human) Q9BT78, (Mouse) O88544, (Rat) Q68FS2
Entrez Gene ID: (Human) 51138, (Mouse) 26891, (Rat) 360915
Molecular Function:
protease
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