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Proteintech
COQ3 Polyclonal Antibody
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Product Details
28051-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
COQ3 Fusion Protein Ag27740 (174-369 aa encoded by BC015634)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Amount
49.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: IDPVDENIK TAQCHKSFDP VLDKRIEYRV CSLEEIVEET AETFDAVVAS EVVEHVIDLE TFLQCCCQVL KPGGSLFITT INKTQLSYAL GIVFSEQIAS IVPKGTHTWE KFVSPETLES ILESNGLSVQ TVVGMLYNPF SGYWHWSENT SLNYAAYAVK SRVQEHPASA EFVLKGETEE LQANACTNPA VHEKLKK (174-369 aa encoded by BC015634)
Target Information
Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes. This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 gene product is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 2-polyprenyl-6-hydroxyphenol methylase; 2-polyprenyl-6-hydroxyphenyl methylase; 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; 3-demethylubiquinol 3-O-methyltransferase; 3-demethylubiquinone 3-O-methyltransferase; 3-demethylubiquinone-10 3-methyltransferase; 3-demethylubiquinone-9 3-methyltransferase; Coenzyme Q (ubiquinone); coenzyme Q3 homolog methyltransferase; coenzyme Q3 homolog, methyltransferase; DHHB methyltransferase; DHHB-MT; DHHB-MTase; dihydroxyhexaprenylbenzoate methyltransferase; hexaprenyldihydroxybenzoate methyltransferase, mitochondrial; methyltransferase COQ3; Polyprenyldihydroxybenzoate methyltransferase; Ubiquinone biosynthesis O-methyltransferase, mitochondrial; unnamed protein product
Gene Aliases: 4732433J24; bA9819.1; C77934; COQ3; DHHBMT; DHHBMTASE; UG0215E05
UniProt ID: (Human) Q9NZJ6, (Mouse) Q8BMS4
Entrez Gene ID: (Human) 51805, (Mouse) 230027
protein binding
methyltransferase activity
O-methyltransferase activity
polyprenyldihydroxybenzoate methyltransferase activity
transferase activity
3-demethylubiquinone-n 3-O-methyltransferase activity
3-demethylubiquinone 3-O-methyltransferase activity
hexaprenyldihydroxybenzoate methyltransferase activity
2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity
3-demethylubiquinone-9 3-O-methyltransferase activity
methyltransferase
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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