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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
2.5 µg/mL | View 1 publication 1 publication |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Published species |
Not Applicable |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Synthetic peptide directed towards the C-terminal of human CORIN |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Protein A |
Storage buffer |
PBS with 2% sucrose |
Contains |
0.09% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2576316 |
Peptide sequence: HPRYSRAVVD YDISIVELSE DISETGYVRP VCLPNPEQWL EPDTYCYITG
Sequence homology: Cow: 79%; Guinea Pig: 79%; Horse: 86%; Human: 100%; Mouse: 79%; Pig: 86%; Rabbit: 86%; Rat: 92%
CORIN is a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. CORIN converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Atrial natriuretic peptide-converting enzyme; Atrial natriuretic peptide-converting enzyme, 100 kDa soluble fragment; Atrial natriuretic peptide-converting enzyme, 160 kDa soluble fragment; Atrial natriuretic peptide-converting enzyme, 180 kDa soluble fragment; Atrial natriuretic peptide-converting enzyme, activated protease fragment; Atrial natriuretic peptide-converting enzyme, N-terminal propeptide; Corin; EC 3.4.21; Heart-specific serine proteinase ATC2; MGC119742; pro-ANP-convertase; Pro-ANP-converting enzyme; PRSC; serine peptidase; serine protease; Transmembrane protease serine 10
Gene Aliases: ATC2; CORIN; CRN; Lrp4; PEE5; TMPRSS10
UniProt ID: (Human) Q9Y5Q5
Entrez Gene ID: (Human) 10699
Molecular Function:
apolipoprotein
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