Proteintech

CORO1C Polyclonal Antibody

View all (8) Coronin 3 antibodies

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CORO1C Antibody in Western Blot (WB) — SGC-7901 cells were subjected to SDS PAGE followed by western blot with 14749-1-AP (CORO1C antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

CORO1C Antibody in Western Blot (WB) — Mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 14749-1-AP (CORO1C antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

CORO1C Antibody in Western Blot (WB) — Human heart tissue were subjected to SDS PAGE followed by western blot with 14749-1-AP (CORO1C antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

CORO1C Antibody in Western Blot (WB) — Mouse heart tissue were subjected to SDS PAGE followed by western blot with 14749-1-AP (CORO1C antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

CORO1C Antibody in Western Blot (WB) — SGC-7901 cells were subjected to SDS PAGE followed by western blot with 14749-1-AP (CORO1C antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

CORO1C Antibody in Western Blot (WB) — HeLa cells were subjected to SDS PAGE followed by western blot with 14749-1-AP (CORO1C antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

CORO1C Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human cervical cancer tissue slide using 14749-1-AP ( CORO1C antibody) at dilution of 1:100 (under 40x lens) heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

CORO1C Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human cervical cancer tissue slide using 14749-1-AP ( CORO1C antibody) at dilution of 1:100 (under 10x lens) heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

CORO1C Antibody in Immunofluorescence (IF) — Immunofluorescent analysis of HepG2 cells, using CORO1C antibody 14749-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IGG (red).

CORO1C Antibody in Immunoprecipitation (IP) — IP result of anti-CORO1C (IP:14749-1-AP, 4ug; Detection:14749-1-AP 1:500) with mouse skeletal muscle tissue lysate 3600ug.

Product Details

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:3000

View 4 publications 4 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

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Immunocytochemistry (ICC)

1:10-1:100

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Immunofluorescence (IF)

1:10-1:100

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Immunoprecipitation (IP)

0.5-4.0 µg

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Miscellaneous PubMed (Misc)

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View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Artificial Control, Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

CORO1C Fusion Protein Ag6488

Conjugate

Unconjugated

Form

Liquid

Concentration

0.22 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Target Information

Coronin 3 is associated with the aggression and metastasis of hepatocellular carcinoma. Coronins are a family of highly evolutionary conserved proteins reportedly involved in the regulation of actin cytoskeletal dynamics, although only coronin 3 has been shown to be related to cancer cell migration.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: coronin 1c; coronin 3; coronin, actin binding protein, 1C; coronin, actin-binding protein, 1C; Coronin-1C; Coronin-3; hCRNN4

Gene Aliases: AL022675; AW455561; AW548837; CORO1C; CRN2; CRNN4; HCRNN4; RGD1564490

UniProt ID: (Human) Q9ULV4, (Mouse) Q9WUM4

Entrez Gene ID: (Human) 23603, (Rat) 501841, (Mouse) 23790

Molecular Function: actin family cytoskeletal protein cytoskeletal protein non-motor actin binding protein

neural crest cell migration regulation of protein phosphorylation negative regulation of protein phosphorylation phagocytosis signal transduction regulation of epithelial cell migration negative regulation of epithelial cell migration regulation of fibroblast migration actin cytoskeleton organization negative regulation of protein kinase activity by regulation of protein phosphorylation establishment of protein localization regulation of focal adhesion assembly negative regulation of focal adhesion assembly activation of GTPase activity regulation of substrate adhesion-dependent cell spreading negative regulation of substrate adhesion-dependent cell spreading regulation of ruffle assembly positive regulation of lamellipodium morphogenesis actin cortical patch assembly

Process(es)

protein binding Rac GTPase binding actin filament binding actin binding