This Antibody was verified by KnockDown to ensure that the antibody binds to the antigen stated. View Details
PA5-21359 targets COX4 in ICC, IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-21359 immunogen is recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 169 (P13073) of COX4.
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Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. COX4 (COX4I1) is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
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Protein Aliases: COX IV-1; COX4; COX4-1; COXIV; Cytochrome c oxidase polypeptide IV; cytochrome c oxidase subunit 4 isoform 1; Cytochrome c oxidase subunit 4 isoform 1, mitochondrial; cytochrome c oxidase subunit IV; Cytochrome c oxidase subunit IV isoform 1; mitochondrial
Gene Aliases: COX IV-1; COX4; COX4-1; COX4I1; COXIV; COXIV-1
UniProt ID: (Human) P13073
Entrez Gene ID: (Human) 1327