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Invitrogen
CPEB1 Polyclonal Antibody
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Product Details
PA5-20561
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A 14 amino acid peptide from near the amino terminus of human CPEB1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
A suggested positive control is rat brain tissue lysate.
PA5-20561 can be used with blocking peptide PEP-0681.
Target Information
This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the nuclear membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the nuclear membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CEBP; CPE-binding protein 1; CPE-BP1; CPEB; CPEB-1; Cytoplasmic polyadenylation element-binding protein 1; FLJ13203; h-CEBP; mCPEB-1; MGC34136; MGC60106
Gene Aliases: AU024112; CPE-BP1; CPEB; CPEB-1; CPEB1; h-CPEB; hCPEB-1; mCPEB
UniProt ID: (Human) Q9BZB8, (Mouse) P70166, (Rat) P0C279
Entrez Gene ID: (Human) 64506, (Mouse) 12877, (Rat) 293056
mRNA processing
translation
negative regulation of cell proliferation
positive regulation of neuron projection development
positive regulation of cell migration
cellular response to insulin stimulus
positive regulation of translation
mRNA transport
positive regulation of nitric-oxide synthase biosynthetic process
cellular response to lipopolysaccharide
cellular response to amino acid stimulus
cellular response to hypoxia
negative regulation of cytoplasmic translation
regulation of translation
synaptonemal complex assembly
negative regulation of translation
regulation of neuronal synaptic plasticity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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