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Invitrogen
CPEB2 Polyclonal Antibody
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Product Details
PA5-30938
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human CPEB2. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: Raji, K562.
Predicted reactivity: Mouse (95%), Pig (81%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene is highly similar to cytoplasmic polyadenylation element binding protein (CPEB), an mRNA-binding protein that regulates cytoplasmic polyadenylation of mRNA as a trans factor in oogenesis and spermatogenesis. Studies of the similar gene in mice suggested a possible role of this protein in transcriptionally inactive haploid spermatids. Alternatively spliced transcript variants encoding distinct isoforms have been described.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CPE-binding protein 2; CPE-BP2; Cytoplasmic polyadenylation element-binding protein 2
Gene Aliases: A630055H10Rik; CPE-BP2; CPEB-2; CPEB2; hCPEB-2
UniProt ID: (Human) Q7Z5Q1
Entrez Gene ID: (Human) 132864, (Mouse) 231207
nucleotide binding
translation repressor activity, nucleic acid binding
mRNA 3'-UTR binding
GTPase inhibitor activity
translation factor activity, RNA binding
mRNA 3'-UTR AU-rich region binding
ribosome binding
ribosomal large subunit binding
ribosomal small subunit binding
poly(A) RNA binding
nucleic acid binding
RNA binding
protein binding
poly-pyrimidine tract binding
mRNA polyadenylation factor
translation
cellular response to insulin stimulus
negative regulation of GTPase activity
cellular response to oxidative stress
cellular response to arsenic-containing substance
cellular response to hypoxia
negative regulation of cytoplasmic translational elongation
negative regulation of cytoplasmic translation
regulation of translation
negative regulation of translational elongation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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