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Invitrogen
CPSF3 Polyclonal Antibody
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Product Details
PA5-57005
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human CPSF3. Recombinant protein control fragment (Product #RP-96050).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: PFNLLCYQLQ KLTGDVEELE IQEKPALKVF KNITVIQEPG MVVLEWLANP SNDMYADTVT TVILEVQSNP KIRKGAVQK
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%.
Target Information
Most eukaryotic mRNA precursors (pre-mRNAs) undergo extensive maturational processing, including cleavage and polyadenylation at the 3-prime end. CPSF3 encodes the 73-kD subunit of the cleavage and polyadenylation specificity factor (CPSF) and is the pre-mRNA 3-prime-end-processing endonuclease (Mandel et al., 2006).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cleavage and polyadenylation specific factor 3, 73kDa; cleavage and polyadenylation specificity factor 3; Cleavage and polyadenylation specificity factor 73 kDa subunit; Cleavage and polyadenylation specificity factor subunit 3; CPSF; CPSF 73 kDa subunit; mRNA 3'-end-processing endonuclease CPSF-73; YSH1
Gene Aliases: CPSF-73; CPSF3; CPSF73
UniProt ID: (Human) Q9UKF6, (Mouse) Q9QXK7
Entrez Gene ID: (Human) 51692, (Mouse) 54451, (Rat) 298916
mRNA splicing, via spliceosome
termination of RNA polymerase II transcription
mRNA polyadenylation
mRNA cleavage
mRNA 3'-end processing by stem-loop binding and cleavage
mRNA export from nucleus
mRNA 3'-end processing
RNA phosphodiester bond hydrolysis, endonucleolytic
mRNA processing
biological_process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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