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CREBBP Polyclonal Antibody

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CREBBP Polyclonal Antibody

Product Details

HA500056

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide within C-terminal human CREBBP.
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Amount

100 µg

Purification

Antigen affinity chromatography

Storage buffer

TBS, pH 7.4, with 0.2% BSA, 50% glycerol

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

CBP for CREB-binding protein is a 265 kDa nuclear protein which probably has many of the properties expected of a CREB co-activator. It shows substantial sequence homology with p300.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: CBP; CREBBP; CREB-binding protein; Histone lysine acetyltransferase CREBBP; Protein lactyltransferas CREBBP; Protein-lysine acetyltransferase CREBBP; unnamed protein product

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Gene Aliases: AW558298; CBP; CBP/p300; CREBBP; KAT3A; MKHK1; p300/CBP; RSTS; RSTS1; RTS

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UniProt ID: (Human) Q92793

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Entrez Gene ID: (Human) 1387, (Mouse) 12914, (Rat) 54244

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Function(s)
transcription coactivator binding p53 binding chromatin binding damaged DNA binding transcription cofactor activity transcription coactivator activity transcription corepressor activity histone acetyltransferase activity protein binding zinc ion binding acetyltransferase activity transferase activity transferase activity, transferring acyl groups chromatin DNA binding MRF binding histone acetyltransferase activity (H3-K18 specific) histone acetyltransferase activity (H3-K27 specific) metal ion binding tau protein binding RNA polymerase II sequence-specific DNA binding transcription factor binding peptide-lysine-N-acetyltransferase activity peptide lactyltransferase (CoA-dependent) activity DNA-binding transcription factor binding RNA polymerase II regulatory region sequence-specific DNA binding core promoter proximal region sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II transcription factor binding transcriptional repressor activity, RNA polymerase II transcription factor binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding DNA binding transcription factor activity, sequence-specific DNA binding transcription factor binding activating transcription factor binding peroxisome proliferator activated receptor binding SMAD binding histone modifying enzyme
Process(es)
negative regulation of transcription from RNA polymerase II promoter double-strand break repair via homologous recombination response to hypoxia stimulatory C-type lectin receptor signaling pathway chromatin remodeling regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter protein acetylation signal transduction I-kappaB kinase/NF-kappaB signaling regulation of smoothened signaling pathway negative regulation of transcription from RNA polymerase I promoter N-terminal peptidyl-lysine acetylation positive regulation of transforming growth factor beta receptor signaling pathway protein destabilization cellular response to nutrient levels cellular response to UV homeostatic process embryonic digit morphogenesis positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter rhythmic process protein stabilization protein-containing complex assembly protein K48-linked deubiquitination energy homeostasis regulation of cellular response to heat positive regulation of protein localization to nucleus positive regulation of double-strand break repair via homologous recombination transcription, DNA-templated transcription from RNA polymerase II promoter cell proliferation histone acetylation germ-line stem cell population maintenance positive regulation of sequence-specific DNA binding transcription factor activity positive regulation of G1/S transition of mitotic cell cycle response to interleukin-1
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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