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Invitrogen
CREBZF Polyclonal Antibody
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FIGURE: 1 / 1
CREBZF Antibody (PA5-92014) in WB
Western blot analysis of CREBZF in extracts of various cell lines. Samples were incubated with CREBZF Polyclonal antibody (Product # PA5-92014) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 1s.
Product Details
PA5-92014
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-354 of human CREBZF (NP_0010347071)
Conjugate
Form
Liquid
Concentration
1.79 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: MRHSLTKLLA ASGSNSPTRS ESPEPAATCS LPSDLTRAAA GEEETAAAGS PGRKQQFGDE GELEAGRGSR GGVAVRAPSP EEMEEEAIAS LPGEETEDMD FLSGLELADL LDPRQPDWHL DPGLSSPGPL SSSGGGSDSG GLWRGDDDDE AAAAEMQRFS DLLQRLLNGI GGCSSSSDSG SAEKRRRKSP GGGGGGGSGN DNNQAATKSP RKAAAAAARL NRLKKKEYVM GLESRVRGLA AENQELRAEN RELGKRVQAL QEESRYLRAV LANETGLARL LSRLSGVGLR LTTSLFRDSP AGDHDYALPV GKQKQDLLEE DDSAGGVCLH VDKDKVSVEF CSACARKASS SLKM; Positive Samples: LO2, 293T, HeLa, U-87MG, K-562, Mouse brain, Mouse heart, Rat brain; Cellular Location: Nucleus
Target Information
Strongly activates transcription when bound to HCFC1. Suppresses the expression of HSV proteins in cells infected with the virus in a HCFC1-dependent manner. Also suppresses the HCFC1-dependent transcriptional activation by CREB3 and reduces the amount of CREB3 in the cell. Able to down-regulate expression of some cellular genes in CREBZF-expressing cells.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CREB/ATF bZIP transcription factor; HCF-binding transcription factor Zhangfei; host cell factor- or C1-binding transcription factor; Host cell factor-binding transcription factor Zhangfei; SHP-interacting leucine zipper protein; small heterodimer partner-interacting leucine zipper; Tyrosine kinase-associated leucine zipper protein LAZip; tyrosine kinase-associated leucine zipper protein LAZipII; unnamed protein product; Zhangfei
Gene Aliases: 1110034C16Rik; 6330417B10Rik; CREBZF; LAZip; LAZipII; RGD1565584; SMILE; ZF
UniProt ID: (Human) Q9NS37, (Mouse) Q91ZR3
Entrez Gene ID: (Human) 58487, (Mouse) 233490, (Rat) 293112
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
response to virus
ATF6-mediated unfolded protein response
negative regulation of gene expression, epigenetic
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of sequence-specific DNA binding transcription factor activity
integrated stress response signaling
transcription, DNA-templated
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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