|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide: L(160) V G K A D E K A S E H H S P Q A(176)|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-4325 detects CRG-L2 in human samples.
PA1-4325 has been successfully used in Western blotting procedures. The predicted molecular weight is 48 kDa. By Western blot, this antibody detects a protein often above ~50 kDa representing CRG-L2. This protein can form dimers.
PA1-4325 immunizing peptide corresponds to amino acid residues 160-176 of human CRG-L2.
A novel gene, CRG-L2 (Cancer related gene-Liver 2) displays high expression in murine and human hepatocellular carcinomas (HCC). Its restricted expression in normal tissues and unique early upregulation during tumor development make CRG-L2 an excellent candidate as a new clinical marker of HCC.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.