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Corticotropin-releasing hormone (CRH; 122560) is a 41-amino acid peptide synthesized in the hypothalamus, and play a role in the neuroregulation, responses to stress and immune challenge. Corticotropin Releasing Factor Receptor 2 (CRHR2) was the receptor of CRH. The sepression of CRHR2 has been reported in various regions of the brain as well as in placenta, umbilical vein, heart, epididymis, gastrointestinal tract, adrenal and skeletal muscle.
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Protein Aliases: corticotrophin releasing hormone receptor 2; corticotropin releasing factor receptor type 2 beta; corticotropin-releasing factor 2; Corticotropin-releasing factor receptor 2; corticotropin-releasing factor receptor subtype 2; Corticotropin-releasing hormone receptor 2; CRF 2 receptor; CRF-R 2; CRF-R-2; CRF-R2; CRF-RB; CRF2; CRF2 receptor, beta isoform; CRFR-2; CRH receptor 2 variant B; CRH-R 2; CRH-R-2; CRH-R2; Crh2 receptor
Gene Aliases: CRF-R2; CRF-RB; CRF2; CRF2R; CRFR2; CRFR2alpha; CRFR2beta; CRH2R; CRHR2; HM-CRF
Molecular Function: transmembrane signal receptor