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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • CRMP3 Antibodies

          Fabgennix

          CRMP3 Polyclonal Antibody, FITC

          View all (11) CRMP3 antibodies

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          Cite CRMP3 Polyclonal Antibody, FITC

          CRMP3 Polyclonal Antibody, FITC

          Product Details

          DRP4-FITC

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          -

          ELISA (ELISA)

          1:10,000
          -

          Immunoprecipitation (IP)

          1:50-1:250
          -
          Product Specifications

          Species Reactivity

          Cat, Human, Mouse, Non-human primate, Pig, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Synthetic peptide corresponding to amino acids 509-527 of Mouse CRMP3. The peptide was covalently modified to achieve the desired antigenicity before coupling to carrier protein.Sequence:PAKPGSGTQARASCSGKIS
          View immunogen

          Conjugate

          FITC FITC FITC

          Excitation/Emission Max

          498/517 nm View spectra spectra

          Form

          Liquid

          Concentration

          0.5-1.5 mg/mL

          Purification

          Affinity chromatography

          Storage buffer

          proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C, store in dark

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          Collapsin response mediator proteins (CRMPs), including CRMP-1 (DRP-1), CRMP-2 (DRP-2 or TOAD64), CRMP-3 (DRP-4), CRMP-4 (DRP-3) and CRMP-5 (DRP-5), mediate signal transduction after exposure of neural cells to the axon guidance molecule Semaphorin 3A (SEMA3A)/collapsin. CRMPs are present in the developing cerebral cortex and neocortical neurons and are responsive to SEMA3A. In the adult brain, the expression of CRMPs is dramatically downregulated. However, they remain expressed in structures that retain their capacity for differentiation and plasticity. CRMP-3 is expressed transiently in developing spinal cord and selectively in the postnatal cerebellum.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Collapsin response mediator protein 3; CRMP-3; dihydropyrimidinase-like 4; Dihydropyrimidinase-related protein 4; DRP-4; ULIP-4; ULIP4 protein; unc-33-like phosphoprotein 4; UNC33-like phosphoprotein 4

          View more View less

          Gene Aliases: AI173505; CRMP-3; CRMP3; DPY4; Dpys4; DPYSL4; DRP-4; ULIP4

          View more View less

          UniProt ID: (Human) O14531, (Rat) Q62951

          View more View less

          Entrez Gene ID: (Human) 10570, (Pig) 100512868, (Rat) 25417, (Mouse) 26757

          View more View less

          Function(s)
          protein binding hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds filamin binding hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides phosphoprotein binding hydrolase activity hydrolase
          Process(es)
          nervous system development neuron death neuron projection guidance pyrimidine nucleobase catabolic process neuron development
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
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          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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