DPYSL3 is necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. DPYSL3 plays a role in axon guidance, neuronal growth cone collapse and cell migration.
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Protein Aliases: Collapsin response mediator protein 4; collapsin response mediator protein 4 long; CRMP-4; dihydropyrimidinase-like 3; Dihydropyrimidinase-related protein 3; DRP-3; testicular secretory protein Li 7; TOAD-64/Ulip/CRMP; TOAD-64/Ulip/CRMP protein 4b; tuc-4; TUC-4b; ULIP-1; Unc-33-like phosphoprotein 1
Gene Aliases: CRMP-4; CRMP4; DPYSL3; DRP-3; DRP3; LCRMP; TUC-4b; TUC4; ULIP; ULIP-1; ULIP1
Molecular Function: hydrolase