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Invitrogen
CROT Polyclonal Antibody
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Product Details
PA5-21650
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human CROT. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: 293T, A431, HeLa, HepG2, Raji, mouse liver.
Predicted reactivity: Mouse (80%), Pig (80%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
CROT encodes a member of the carnitine/choline acetyltransferase family. The encoded protein converts 4, 8-dimethylnonanoyl-CoA to its corresponding carnitine ester. This transesterification occurs in the peroxisome and is necessary for transport of medium- and long- chain acyl-CoA molecules out of the peroxisome to the cytosol and mitochondria. The protein thus plays a role in lipid metabolism and fatty acid beta-oxidation. Alternatively spliced transcript variants have been described.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: COT; peroxisomal carnitine acyltransferase; Peroxisomal carnitine O-octanoyltransferase
Gene Aliases: 1200003H03Rik; COT; CROT
UniProt ID: (Human) Q9UKG9, (Mouse) Q9DC50
Entrez Gene ID: (Human) 54677, (Mouse) 74114
generation of precursor metabolites and energy
fatty acid metabolic process
fatty acid beta-oxidation
carnitine metabolic process
response to organonitrogen compound
fatty acid transport
coenzyme A metabolic process
fatty acid beta-oxidation using acyl-CoA oxidase
response to drug
medium-chain fatty acid metabolic process
lipid metabolic process
transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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