PA1-23419 detects CRTH2 in human samples.
PA1-23419 has been successfully used in ELISA and Western blot procedures.
PA1-23419 immunogen is a synthetic peptide corresponding to the C-terminal residues D(329) D S E L G G A G S S R R R R T S S T A(348) of CRTH2.
CRTH2 (chemoattractant receptor-homologous molecule), which is also known as the putative G protein-coupled receptor (GPR44), is expressed on Th2 cells and is a novel member of the G protein-coupled leukocyte chemoattractant receptor family, which is selectively expressed in Th2 but not Th1 lineage cells. CRTH2 is selectively expressed in vivo in an activated state of Th2 cells including allergen-responsive Th2 cells, suggesting its pivotal roles in ongoing Th2-type immune reactions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD294; chemoattractant receptor homologous molecule expressed on T helper type 2 cells; Chemoattractant receptor-homologous molecule expressed on Th2 cells; Crth2; G protein-coupled receptor 44; G-protein coupled receptor 44; Grp45; MGC130436; Prostaglandin D2 receptor 2; putative G-protein coupled receptor 44
Gene Aliases: CD294; CRTH2; DL1R; DP2; GPR44; PTGDR2
UniProt ID: (Human) Q9Y5Y4
Entrez Gene ID: (Human) 11251