Recommended positive controls: 293T, Jurkat, Raji, mouse brain.
Predicted reactivity: Human (99%), Mouse (81%), Rat (82%), Dog (87%), Pig (80%), Rhesus Monkey (96%), Bovine (87%), Guinea pig (85%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. The former class is also called phylogenetically-restricted crystallins. This gene encodes a taxon-specific crystallin protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family. Unlike other mammalian species, in humans, lens expression is low. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One pseudogene is known to exist.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: crystallin, zeta (quinone reductase); nadph quinone reductase; NADPH:quinone reductase; Quinone oxidoreductase; quinone reductase; zeta crystallin; Zeta-crystallin
Gene Aliases: CRYZ; Sez9