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Proteintech
CSE1L Polyclonal Antibody
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Product Details
22219-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CSE1L Fusion Protein Ag17556 (627-971 aa encoded by BC109313)
Conjugate
Form
Liquid
Concentration
0.19 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: RITCKANPA AVVNFEEALF LVFTEILQND VQEFIPYVFQ VMSLLLETHK NDIPSSYMAL FPHLLQPVLW ERTGNIPALV RLLQAFLERG SNTIASAAAD KIPGLLGVFQ KLIASKANDH QGFYLLNSII EHMPPESVDQ YRKQIFILLF QRLQNSKTTK FIKSFLVFIN LYCIKYGALA LQEIFDGIQP KMFGMVLEKI IIPEIQKVSG NVEKKICAVG ITKLLTECPP MMDTEYTKLW TPLLQSLIGL FELPEDDTIP DEEHFIDIED TPGYQTAFSQ LAFAGKKEHD PVGQMVNNPK IHLAQSLHKL STACPGRVPS MVSTSLNAEA LQYLQGYLQA ASVTLL (627-971 aa encoded by BC109313)
Target Information
Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Cellular apoptosis susceptibility protein; Chromosome segregation 1-like protein; CSE1 chromosome segregation 1 like; CSE1 chromosome segregation 1-like; Exp2; Exportin-2; Importin-alpha re-exporter; MGC117283; MGC130036; MGC130037
Gene Aliases: 2610100P18Rik; AA407533; Capts; CAS; CSE1; CSE1L; XPO2
UniProt ID: (Human) P55060, (Mouse) Q9ERK4
Entrez Gene ID: (Human) 1434, (Mouse) 110750
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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