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Invitrogen
CSF2RA Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-86879
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to residues in Human CSF2RA.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Purity is > 95% by SDS-PAGE.
Target Information
The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. This gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encoding different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha-GM-CSF receptor; CD116 antigen; colony stimulating factor 2 receptor alpha chain; colony stimulating factor 2 receptor alpha subunit; colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage); CSF 2R; GM CSF R alpha; GM-CSF receptor alpha subunit; GM-CSF receptor alpha subunit; cytokine receptor; colony stimulating factor 2 receptor alpha low-affinity (granulocyte-macrophage); GM-CSF-R-alpha; GM-CSFRalpha; GMCSFR-alpha; GMR-alpha; granulocyte-macrophage colony stimulating receptor alpha; granulocyte-macrophage colony-stimulating factor receptor alpha chain; growth factor receptor; CD116 antigen; GM-CSF; MGC3848; MGC4838; unnamed protein product
Gene Aliases: alphaGMR; CD116; CDw116; CSF2R; CSF2RAX; CSF2RAY; CSF2RX; CSF2RY; Csfgmra; GM-CSF-R-alpha; GM-CSF-Ra; GM-CSFR; GMCSFR; GMCSFR-alpha; GMR; GMR-alpha; SMDP4
UniProt ID: (Human) P15509, (Mouse) Q00941
Entrez Gene ID: (Human) 1438, (Mouse) 12982, (Rat) 652957
JAK-STAT cascade
granulocyte-macrophage colony-stimulating factor signaling pathway
granulocyte colony-stimulating factor signaling pathway
positive regulation of leukocyte proliferation
cellular response to granulocyte macrophage colony-stimulating factor stimulus
cell surface receptor signaling pathway
positive regulation of cell proliferation
cytokine-mediated signaling pathway
positive regulation of JAK-STAT cascade
growth hormone receptor signaling pathway
response to ethanol
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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