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Invitrogen
CSF2RB Polyclonal Antibody
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FIGURE: 1 / 1
CSF2RB Antibody (PA5-87951) in WB
Western blot analysis of CSF2RB in various lysates. Samples were incubated with CSF2RB Polyclonal antibody (Product # PA5-87951) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 30s.
Product Details
PA5-87951
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein (or fragment)
Conjugate
Form
Liquid
Concentration
1.17 mg/mL
Amount
117 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Samples: LO2, Mouse spleen, Mouse liver, Mouse lung, Mouse thymus, Rat liver; Cellular Location: Membrane, Single-pass type I membrane protein
Target Information
The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: beta c; beta common cytokine receptor; beta-GM-CSF receptor; CD antigen CD131; CD131; CD131 antigen; CDw131; colony stimulating factor 2 receptor beta common subunit; colony stimulating factor 2 receptor, beta 1, low-affinity (granulocyte-macrophage); colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage); Colony-stimulating factor 2 receptor subunit beta-2; colony-stimulating factor-2 receptor, beta, low-affinity; common beta chain; CSF2RB; Cytokine receptor common subunit beta; GM-CSF/IL-3/IL-5 receptor common beta subunit; GM-CSF/IL-3/IL-5 receptor common beta-chain; IL-3 RB; IL-3 Receptor beta; IL-3 receptor class 2 subunit beta; IL-3R class 2 subunit beta; IL3R beta; interleukin 3 receptor/granulocyte-macrophage colony stimulating factor 3 receptor, beta (high affinity); Interleukin-3 receptor class 2 subunit beta; Interleukin-3 receptor class II beta chain; unnamed protein product
Gene Aliases: Ai2ca; AI848964; AIC2A; AIC2B; Bc; betaGMR; BetaIl3; Bil3; CD131; CDw131; CSF2RB; Csf2rb1; Csf2rb2; Csfgmrb; Il3r; IL3RB; Il3rb1; Il3rb2; IL5RB; SMDP5
UniProt ID: (Human) P32927, (Mouse) P26955, (Mouse) P26954
Entrez Gene ID: (Human) 1439, (Mouse) 12983, (Mouse) 12984
signal transduction
JAK-STAT cascade
respiratory gaseous exchange
immunoglobulin mediated immune response
cytokine-mediated signaling pathway
response to lipopolysaccharide
cellular response to interleukin-3
interleukin-5-mediated signaling pathway
interleukin-3-mediated signaling pathway
granulocyte-macrophage colony-stimulating factor signaling pathway
positive regulation of leukocyte proliferation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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