Positive Control: 293T, A431, H1299, Molt-4, Raji
Predicted Reactivity: Mouse (98%), Rat (98%), Zebrafish (89%), Pig (97%), Chicken (94%), Rhesus Monkey (100%), Bovine (98%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
C-terminal Src kinase (CSK) is a non-receptor protein tyrosine kinase that plays an important role in the regulation of cell growth, differentiation, migration, and immune responses. CSK phosphorylates tyrosine residues located in the C-terminal tails of Src-family kinases including LCK, SRC, HCK, FYN, LYN, CSK, and YES1. CSK is expressed ubiquitously as a protein of approximately 50 KDa in cytosol, but a fraction distributes to lipid rafts due to interaction with the lipid raft-associated protein PAG (Csk-binding protein).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C-Src kinase; c-src tyrosine kinase; CSK; MGC117393; Protein-tyrosine kinase CYL; Tyrosine-protein kinase CSK
Gene Aliases: CSK
UniProt ID: (Human) P41240
Entrez Gene ID: (Human) 1445