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Invitrogen
CSMD1 Polyclonal Antibody
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Product Details
PA5-50645
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to residues near the C terminal of human CUB and Sushi multiple domains 1
Conjugate
Form
Liquid
Concentration
3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 40% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody detects endogenous levels of total CSMD1 protein.
Target Information
CSMD1 CUB and Sushi multiple domains 1 is a protein that in humans is encoded by the CSMD1gene. It is a potential tumour suppressor, the deletion of which may result in head and neck carcinomas behaving more aggressively. CSMD1 is part of the complement system that defends against pathogens through either the classical pathway or the alternative pathway. Located primarily in nerve growth cones, CSMD1 blocks the classical pathway of the immune system and is thought to be involved in tumor suppression, as defects in the gene encoding CSMD1 are associated with squamous cell carcinomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CUB and sushi domain-containing protein 1; CUB and sushi multiple domains protein 1; protein phosphatase 1, regulatory subunit 24
Gene Aliases: B930082H09; CSMD1; KIAA1890; mKIAA1890; PPP1R24; UNQ5952/PRO19863
UniProt ID: (Human) Q96PZ7, (Mouse) Q923L3
Entrez Gene ID: (Human) 64478, (Mouse) 94109
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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