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Invitrogen
CSRP3 Polyclonal Antibody
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FIGURE: 1 / 2
CSRP3 Antibody (PA5-109602) in IHC (P)
Immunohistochemistry analysis of CSRP3 in paraffin-embedded mouse heart. Samples were incubated with CSRP3 Polyclonal antibody (Product # PA5-109602) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
PA5-109602
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein (or fragment)
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Amount
20 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
This gene encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in this gene are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cardiac LIM domain protein; Cardiac LIM protein; CRP3; CSRP3 cysteine and glycine-rich protein 3; Cysteine and glycine-rich protein 3; cysteine and glycine-rich protein 3 (cardiac LIM protein); Cysteine-rich protein 3; hhsLIMP3; LIM domain only 4; LIM domain protein, cardiac; MGC14488; MGC61993; Muscle LIM protein; unnamed protein product
Gene Aliases: CLP; CMD1M; CMH12; CRP3; CSRP3; LMO4; MLP; MMLP
UniProt ID: (Human) P50461, (Mouse) P50462, (Rat) P50463
Entrez Gene ID: (Human) 8048, (Mouse) 13009, (Rat) 117505
regulation of the force of heart contraction
cardiac muscle hypertrophy
cellular calcium ion homeostasis
inflammatory response
heart development
muscle organ development
skeletal muscle tissue development
insulin receptor signaling pathway
cell differentiation
T-tubule organization
protein localization to organelle
detection of muscle stretch
glucose homeostasis
sarcomere organization
negative regulation of myoblast differentiation
positive regulation of myoblast differentiation
positive regulation of transcription from RNA polymerase II promoter
muscle cell cellular homeostasis
cardiac muscle tissue development
cardiac myofibril assembly
cardiac muscle contraction
muscle tissue development
establishment of protein localization to organelle
phospholipase C/protein kinase C signal transduction
regulation of protein localization to plasma membrane
negative regulation of actin filament severing
positive regulation of actin filament severing
multicellular organism development
positive regulation of myotube differentiation
positive regulation of sequence-specific DNA binding transcription factor activity
blood vessel remodeling
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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