Invitrogen

CTGF Monoclonal Antibody (CL5339)

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CTGF Antibody in Immunohistochemistry (IHC) — Immunohistochemical analysis of CTGF in human lymph node using a CTGF monoclonal antibody (Product # MA5-31420). The analysis shows absence of positivity in lymphoid cells as expected (negative control).

CTGF Antibody in Western Blot (WB) — Western blot analysis of CTGF by a CTGF monoclonal antibody (Product # MA5-31420). Analysis in human cell line U-251 MG.

Product Details

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

Western Blot (WB)

1 µg/mL

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host / Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

CL5339

Immunogen

Recombinant protein corresponding to Human CTGF

Conjugate

Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

RRID

AB_2787056

Product Specific Information

Immunogen sequence: LPSPDCPFPR RVKLPGKCCE EWVCDEPKDQ TVVGPALAAY RLEDTFGPDP TMIRANCLVQ TTEWSACSKT CGMG

Target Information

Connective Tissue Growth Factor (CTGF), also called CCN2, is a member of the CCN family. CTGF is a secreted protein produced by umbilical veins and vascular endothelial cells. CTGF possesses an Insulin-like Growth Factor (IGF)-binding domain, a thrombospondin type 1 domain, and a cysteine knot region. CTGF plays important roles in the proliferation and differentiation of chondrocytes, induces angiogenesis, and promotes cell adhesion in fibroblasts, endothelial, and epithelial cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 2-Nov; CCN family member 2; Cellular communication network factor 2; Connective tissue growth factor; Connective tissue growth factor precursor (CTGF) (FISP-12 protein) (Hypertrophic chondrocyte-specific protein 24); Connective tissue growth-related protein; fibroblast inducible secreated protein; fibroblast inducible secreted protein; H-CTGF; hypertrophic chondrocyte-specific gene product 24; Hypertrophic chondrocyte-specific protein 24; IBP-8; IGF-binding protein 8; IGFBP-8; Insulin-like growth factor-binding protein 8; MGC102839; Protein FISP-12

Gene Aliases: betaIG-M2; CCN2; CTGF; CTGRP; Fisp-12; Fisp12; HCS24; IGFBP8; NOV2

UniProt ID: (Human) P29279, (Mouse) P29268, (Rat) Q9R1E9

Entrez Gene ID: (Human) 1490, (Mouse) 14219, (Rat) 64032

Molecular Function: growth factor signaling molecule