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Invitrogen

CTGF Monoclonal Antibody (CL5339)

View all (22) CTGF antibodies
635D49A6-4B57-425E-8DC4-6BA1AEB7B473 Created with sketchtool. Datasheet
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635D49A6-4B57-425E-8DC4-6BA1AEB7B473 Created with sketchtool. Datasheet
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Product Details

Tested Applications
Dilution
Immunohistochemistry (Paraffin) (IHC (P))
1:200-1:500
Western Blot (WB)
1 µg/mL
Product Specifications
Species Reactivity
Human, Mouse, Rat
Host / Isotype
Mouse / IgG1
Class
Monoclonal
Type
Antibody
Clone
CL5339
Immunogen
Recombinant protein corresponding to Human CTGF
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Product Specific Information

Immunogen sequence: LPSPDCPFPR RVKLPGKCCE EWVCDEPKDQ TVVGPALAAY RLEDTFGPDP TMIRANCLVQ TTEWSACSKT CGMG

Target Information

CTGF (connective tissue growth factor) is a 38kDa, cysteine-rich, secreted peptide. It is a new member of the peptide family that include serum-induced immediate early gene products, a v-src-induced peptide and a putative proto-oncogene. Among the many functions of the CTGF gene family are embryogenesis, wound healing and regulation of extracellular matrix production.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: CCN family member 2; CCN2; Connective tissue growth factor; Connective tissue growth factor precursor (CTGF) (FISP-12 protein) (Hypertrophic chondrocyte-specific protein 24); Connective tissue growth-related protein; fibroblast inducible secreated protein; fibroblast inducible secreted protein; hypertrophic chondrocyte-specific gene product 24; Hypertrophic chondrocyte-specific protein 24; IBP-8; IGF-binding protein 8; IGFBP-8; IGFBP8; Insulin-like growth factor-binding protein 8; Protein FISP-12

Gene Aliases: CCN2; CTGF; CTGRP; Fisp-12; Fisp12; HCS24; IGFBP8; NOV2

UniProt ID: (Human) P29279, (Mouse) P29268, (Rat) Q9R1E9

Entrez Gene ID: (Human) 1490, (Mouse) 14219, (Rat) 64032

Molecular Function: growth factor signaling molecule

Function(s)
cartilage condensation ossification angiogenesis regulation of cell growth tissue homeostasis transcription initiation from RNA polymerase II promoter cell adhesion cell-matrix adhesion integrin-mediated signaling pathway cell-cell signaling positive regulation of cell proliferation fibroblast growth factor receptor signaling pathway epidermis development response to wounding response to glucose organ senescence positive regulation of gene expression negative regulation of gene expression cell migration cell differentiation lung development regulation of chondrocyte differentiation response to estradiol positive regulation of collagen biosynthetic process response to anoxia intracellular signal transduction chondrocyte proliferation response to amino acid positive regulation of cysteine-type endopeptidase activity involved in apoptotic process response to peptide hormone positive regulation of cell differentiation positive regulation of JNK cascade positive regulation of cell activation response to mineralocorticoid positive regulation of stress fiber assembly cytosolic calcium ion transport positive regulation of cardiac muscle contraction negative regulation of cell death extracellular matrix constituent secretion positive regulation of G0 to G1 transition positive regulation of ERK1 and ERK2 cascade response to fatty acid DNA biosynthetic process reactive oxygen species metabolic process positive regulation of protein phosphorylation positive regulation of cell death connective tissue development response to organic cyclic compound
Process(es)
fibronectin binding integrin binding protein binding insulin-like growth factor binding protein C-terminus binding growth factor activity heparin binding

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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