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Abnova
CTNNA2 Polyclonal Antibody, MaxPab™
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Product Details
H00001496-B01P
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CTNNA2 (NP_004380.2, 1 a.a. approximately 905 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
50 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MTSATSPIIL KWDPKSLEIR TLTVERLLEP LVTQVTTLVN TSNKGPSGKK KGRSKKAHVL AASVEQATQN FLEKGEQIAK ESQDLKEELV AAVEDVRKQG ETMRIASSEF ADDPCSSVKR GTMVRAARAL LSAVTRLLIL ADMADVMRLL SHLKIVEEAL EAVKNATNEQ DLANRFKEFG KEMVKLNYVA ARRQQELKDP HCRDEMAAAR GALKKNATML YTASQAFLRH PDVAATRANR DYVFKQVQEA IAGISNAAQA TSPTDEAKGH TGIGELAAAL NEFDNKIILD PMTFSEARFR PSLEERLESI ISGAALMADS SCTRDDRRER IVAECNAVRQ ALQDLLSEYM NNTGRKEKGD PLNIAIDKMT KKTRDLRRQL RKAVMDHISD SFLETNVPLL VLIEAAKSGN EKEVKEYAQV FREHANKLVE VANLACSISN NEEGVKLVRM AATQIDSLCP QVINAALTLA ARPQSKVAQD NMDVFKDQWE KQVRVLTEAV DDITSVDDFL SVSENHILED VNKCVIALQE GDVDTLDRTA GAIRGRAARV IHIINAEMEN YEAGVYTEKV LEATKLLSET VMPRFAEQVE VAIEALSANV PQPFEENEFI DASRLVYDGV RDIRKAVLMI RTPEELEDDS DFEQEDYDVR SRTSVQTEDD QLIAGQSARA IMAQLPQEEK AKIAEQVEIF HQEKSKLDAE VAKWDDSGND IIVLAKQMCM IMMEMTDFTR GKGPLKNTSD VINAAKKIAE AGSRMDKLAR AVADQCPDSA CKQDLLAYLQ RIALYCHQLN ICSKVKAEVQ NLGGELIVSG LDSATSLIQA AKNLMNAVVL TVKASYVAST KYQKVYGTAA VNSPVVSWKM KAPEKKPLVK REKPEEFQTR VRRGSQKKHI SPVQALSEFK AMDSF
Target Information
Alpha catenin is a member of the b-catenin family of cytosolic proteins. Alpha catenin interacts with N-cadherin and b-catenin on the cytosolic side of adherins junctions to mediate the interaction with the actin cytoskeleton. Alpha catenin is a homodimer in solution, but dissociates to form a 1:1 heterodimer with b-catenin in order to interact with cadherins. It also regulates morphological plasticity of synapses and cerebellar and hippocampal lamination during development. Alpha catenin also functions in the control of the startle modulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Alpha E-catenin; Alpha N-catenin; alpha-catenin; Alpha-catenin-related protein; alpha-E-catenin; alpha-N-catenin; alphaE-catenin; alphaN-catenin; Cadherin-associated protein; cadherin-associated protein, related; cancer/testis antigen 114; catenin; catenin (cadherin associated protein), alpha 1; catenin (cadherin-associated protein), alpha 1, 102kDa; catenin (cadherin-associated protein), alpha 2; catenin alpha 2; Catenin alpha-1; Catenin alpha-2; Catenin alpha1; Catenin alpha2; catenin, alpha 1; Catenin-alpha1; Catenin-alpha2; epididymis secretory sperm binding protein; FLJ36832; FLJ52416; HGNC:2509; NY-REN-13 antigen; Renal carcinoma antigen NY-REN-13; unnamed protein product
Gene Aliases: CAP-R; CAP102; CAPR; Catna1; Catna2; CDCBM9; CT114; CTNNA1; CTNNA2; CTNR; MDBS2; MDPT2
UniProt ID: (Human) P35221, (Human) P26232
Entrez Gene ID: (Human) 1495, (Human) 1496, (Rat) 307505, (Rat) 297357
RNA binding
structural molecule activity
protein binding
beta-catenin binding
cytoskeletal protein binding
vinculin binding
identical protein binding
macromolecular complex binding
gamma-catenin binding
cadherin binding
actin filament binding
structural constituent of cytoskeleton
poly(A) RNA binding
non-motor actin binding protein
ovarian follicle development
apoptotic process
cell adhesion
establishment or maintenance of cell polarity
smoothened signaling pathway
integrin-mediated signaling pathway
neuroblast proliferation
negative regulation of neuroblast proliferation
protein localization
male gonad development
gap junction assembly
cell migration
axon regeneration
regulation of cell proliferation
odontogenesis of dentin-containing tooth
negative regulation of apoptotic process
apical junction assembly
response to estrogen
positive regulation of smoothened signaling pathway
cell motility
cellular response to indole-3-methanol
epithelial cell-cell adhesion
extrinsic apoptotic signaling pathway in absence of ligand
cell-cell adhesion
negative regulation of protein localization to nucleus
negative regulation of cell motility
negative regulation of integrin-mediated signaling pathway
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
cytoskeleton organization
axonogenesis
regulation of neuron projection development
radial glia guided migration of Purkinje cell
cell differentiation
negative regulation of Arp2/3 complex-mediated actin nucleation
dendrite morphogenesis
brain morphogenesis
regulation of synapse structural plasticity
prepulse inhibition
modification of postsynaptic actin cytoskeleton
regulation of neuron migration
actin filament organization
aging
response to organic cyclic compound
cellular protein localization
protein heterooligomerization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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