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Proteintech
CTRP4 Polyclonal Antibody
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Product Details
14023-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CTRP4 Fusion Protein Ag5147 (1-329 aa encoded by BC035628)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Amount
19.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MLPLLLGLL GPAACWALGP TPGPGSSELR SAFSAARTTP LEGTSEMAVT FDKVYVNIGG DFDVATGQFR CRVPGAYFFS FTAGKAPHKS LSVMLVRNRD EVQALAFDEQ RRPGARRAAS QSAMLQLDYG DTVWLRLHGA PQYALGAPGA TFSGYLVYAD ADADAPARGP PAPPEPRSAF SAARTRSLVG SDAGPGPRHQ PLAFDTEFVN IGGDFDAAAG VFRCRLPGAY FFSFTLGKLP RKTLSVKLMK NRDEVQAMIY DDGASRRREM QSQSVMLALR RGDAVWLLSH DHDGYGAYSN HGKYITFSGF LVYPDLAPAA PPGLGASELL (1-329 aa encoded by BC035628)
Target Information
Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. Multiple isoforms of mouse CTRP4 have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: C1q and tumor necrosis factor related protein 4; C1q/TNF-related protein 4; Complement C1q tumor necrosis factor-related protein 4; complement-c1q tumor necrosis factor-related protein 4
Gene Aliases: 0710001E10Rik; 9430004J15Rik; C1QTNF4; CTRP4; ZACRP4
UniProt ID: (Human) Q9BXJ3, (Mouse) Q8R066
Entrez Gene ID: (Human) 114900, (Mouse) 67445, (Rat) 311184
reduction of food intake in response to dietary excess
gene expression
positive regulation of interleukin-6 production
positive regulation of tumor necrosis factor production
positive regulation of interleukin-6-mediated signaling pathway
receptor signaling pathway via STAT
positive regulation of NIK/NF-kappaB signaling
biological_process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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