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Abnova
CTSA Polyclonal Antibody, MaxPab™
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Product Details
H00005476-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CTSA (AAH93009.1, 1 a.a. approximately 480 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MIRAAPPPLF LLLLLLLLLV SWASRGEAAP DQDEIQRLPG LAKQPSFRQY SGYLKGSGSK HLHYWFVESQ KDPENSPVVL WLNGGPGCSS LDGLLTEHGP FLVQPDGVTL EYNPYSWNLI ANVLYLESPA GVGFSYSDDK FYATNDTEVA QSNFEALQDF FRLFPEYKNN KLFLTGESYA GIYIPTLAVL VMQDPSMNLQ GLAVGNGLSS YEQNDNSLVY FAYYHGLLGN RLWSSLQTHC CSQNKCNFYD NKDLECVTNL QEVARIVGNS GLNIYNLYAP CAGGVPSHFR YEKDTVVVQD LGNIFTRLPL KRMWHQALLR SGDKVRMDPP CTNTTAASTY LNNPYVRKAL NIPEQLPQWD MCNFLVNLQY RRLYRSMNSQ YLKLLSSQKY QILLYNGDVD MACNFMGDEW FVDSLNQKME VQRRPWLVKY GDSGEQIAGF VKEFSHIAFL TIKGAGHMVP TDKPLAAFTM FSRFLNKQPY
Target Information
The cathepsin family of proteolytic enzymes include several diverse classes of proteases. Cathepsins B, L, H, K, S and O comprise the cysteine protease class. Cathepsins D and E comprise the aspartyle protease class. The serine protease class includes cathepsin G. Cathepsins function in cellular metabolism and participate in peptide biosynthesis and protein degradation. Cathepsin A, a serine carboxypeptidase, exists in a high molecular weight lysosomal complex with b-galactosidase (b-gal) and a-neuraminidase (Neu1). Cathepsin A functions to protect b-gal and Neu1 from intralysosomal proteolysis. Deficiencies in cathepsin A lead to deficiencies in b-gal and Neu1. The gene encoding human cathepsin A maps to chromosome 20q13.12. Mutations in this gene cause glactosialidosis, a lysosomal storage disorder resulting from the b-gal and Neu1 deficiencies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: beta-galactosidase 2; beta-galactosidase protective protein; Carboxypeptidase C; Carboxypeptidase L; carboxypeptidase Y-like kininase; carboxypeptidase-L; Cathepsin A; deamidase; lysosomal carboxypeptidase A; Lysosomal protective protein; PPCA; Protective protein cathepsin A; Protective protein for beta-galactosidase; urinary kininase
Gene Aliases: CTSA; GLB2; GSL; NGBE; PPCA; PPGB
UniProt ID: (Human) P10619
Entrez Gene ID: (Human) 5476
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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