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Abnova
CUL4A Polyclonal Antibody, MaxPab™
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Product Details
H00008451-D01P
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CUL4A (NP_001008895.1, 1 a.a. approximately 759 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Cell lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MADEAPRKGS FSALVGRTNG LTKPAALAAA PAKPGGAGGS KKLVIKNFRD RPRLPDNYTQ DTWRKLHEAV RAVQSSTSIR YNLEELYQAV ENLCSHKVSP MLYKQLRQAC EDHVQAQILP FREDSLDSVL FLKKINTCWQ DHCRQMIMIR SIFLFLDRTY VLQNSTLPSI WDMGLELFRT HIISDKMVQS KTIDGILLLI ERERSGEAVD RSLLRSLLGM LSDLQVYKDS FELKFLEETN CLYAAEGQRL MQEREVPEYL NHVSKRLEEE GDRVITYLDH STQKPLIACV EKQLLGEHLT AILQKGLDHL LDENRVPDLA QMYQLFSRVR GGQQALLQHW SEYIKTFGTA IVINPEKDKD MVQDLLDFKD KVDHVIEVCF QKNERFVNLM KESFETFINK RPNKPAELIA KHVDSKLRAG NKEATDEELE RTLDKIMILF RFIHGKDVFE AFYKKDLAKR LLVGKSASVD AEKSMLSKLK HECGAAFTSK LEGMFKDMEL SKDIMVHFKQ HMQNQSDSGP IDLTVNILTM GYWPTYTPME VHLTPEMIKL QEVFKAFYLG KHSGRKLQWQ TTLGHAVLKA EFKEGKKEFQ VSLFQTLVLL MFNEGDGFSF EEIKMATGIE DSELRRTLQS LACGKARVLI KSPKGKEVED GDKFIFNGEF KHKLFRIKIN QIQMKETVEE QVSTTERVFQ DRQYQIDAAI VRIMKMRKTL GHNLLVSELY NQLKFPVKPG DLKKRIESLI DRDYMERDKD NPNQYHYVA
Target Information
CUL4A (Cullin 4A) is the ubiquitin ligase component of a multimeric complex involved in the degradation of DNA damage-response proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CUL 4A; CUL-4A; Cul4a protein; Cullin-4A; MGC36573; MGC64071; OTTHUMP00000018753; ubiquitin E3 ligase; unnamed protein product
Gene Aliases: 2810470J21Rik; AW495282; CUL4A
UniProt ID: (Human) Q13619, (Mouse) Q3TCH7
Entrez Gene ID: (Human) 8451, (Mouse) 99375
G1/S transition of mitotic cell cycle
in utero embryonic development
DNA repair
ubiquitin-dependent protein catabolic process
cellular response to DNA damage stimulus
spermatogenesis
cell proliferation
positive regulation of cell proliferation
protein ubiquitination
hemopoiesis
negative regulation of granulocyte differentiation
developmental process
cellular response to UV
somatic stem cell population maintenance
mRNA cleavage involved in gene silencing by miRNA
T cell activation
ribosome biogenesis
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of protein catabolic process
rhythmic process
regulation of protein metabolic process
type I interferon signaling pathway
intrinsic apoptotic signaling pathway
base-excision repair, AP site formation via deaminated base removal
ubiquitin-dependent protein catabolic process via the C-end degron rule pathway
positive regulation of G1/S transition of mitotic cell cycle
regulation of DNA damage checkpoint
regulation of nucleotide-excision repair
viral process
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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