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Proteintech
CWC22 Polyclonal Antibody
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Product Details
26898-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CWC22 Fusion Protein Ag25466 (559-905 aa encoded by BC093954)
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: SLPWSVLEC IKLSEETTTS SSRIFVKIFF QELCEYMGLP KLNARLKDET LQPFFEGLLP RDNPRNTRFA INFFTSIGLG GLTDELREHL KNTPKVIVAQ KPDVEQNKSS PSSSSSASSS SESDSSDSDS DSSDSSSESS SEESDSSSIS SHSSASANDV RKKGHGKTRS KEVDKLIRNQ QTNDRKQKER RQEHGHQETR TERERRSEKH RDQNSRGSNW RDPITKYTSD KDVPSERNNY SRVANDRDQE MHIDLENKHG DPKKKRGERR NSFSENEKHT HRIKDSENFR RKDRSKSKEM NRKHSGSRSD EDRYQNGAER RWEKSSRYSE QSRESKKNQD RRREKSPA (559-905 aa encoded by BC093954)
Target Information
Required for pre-mRNA splicing as component of the spliceosome (PubMed:12226669, PubMed:11991638, PubMed:22961380, PubMed:28502770, PubMed:28076346, PubMed:29360106, PubMed:29301961). Promotes exon-junction complex (EJC) assembly (PubMed:22959432, PubMed:22961380). Hinders EIF4A3 from non-specifically binding RNA and escorts it to the splicing machinery to promote EJC assembly on mature mRNAs. Through its role in EJC assembly, required for nonsense-mediated mRNA decay. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CWC22 spliceosome-associated protein homolog; fSAPb; functional spliceosome-associated protein b; Nucampholin homolog; Pre-mRNA-splicing factor CWC22 homolog
Gene Aliases: CWC22; EIF4GL; fSAPb; KIAA1604; NCM
UniProt ID: (Human) Q9HCG8
Entrez Gene ID: (Human) 57703
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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