|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 19 amino acid peptide from 3rd extracellular domain of human CX3CR1.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||3.8 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
In IHC applications, antigen retrieval using a citrate buffer (pH 6.0) is recommended.
Percent identity with other species by BLAST analysis: Human (100%) Gorilla, Gibbon, Monkey (95%) Marmoset, Mouse, Panda (84%).
Fractalkine, also termed neurotactin, is a membrane-bound CX3C chemokine. Rat CX3CR1, also named RBS11, was first cloned from rat brainstem, pituitary and/or spinal cord cDNA libraries. A G-protein-coupled seven-transmembrane domain receptor, it was recently identified to serve as fractalkine receptor. The human equivalent receptor is known as V28, which has been shown to mediate both the adhesive and migratory functions of fractalkine. Fractalkine and CX3CR1 represent new types of leukocyte trafficking regulators.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.