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Invitrogen
CXCL2 Polyclonal Antibody
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FIGURE: 1 / 3
CXCL2 Antibody (PA5-79110) in WB
Western Blot was performed using Anti-CXCL2 Polyclonal Antibody (Product # PA5-79110) and a 7.8 kDa band corresponding to CXCL2 (C-X-C motif chemokine 2) was observed to upregulate upon lipopolysaccharide treatment to RAW 264.7 cells. Whole cell extracts (40 µg lysate) of RAW 264.7 (Lane 1), LPS treated RAW 264.7 (Lane 2) and RAW 264.7 treated with LPS and secretory inhibitor (Lane 3) in Fig. a and conditioned medium (10uL per well) from untreated RAW 264.7 (Lane 1) and LPS treated RAW 264.7 (Lane 2) in Fig. b were electrophoresed using No... View More
Product Details
PA5-79110
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived rat CXCL2 recombinant protein (Position: S32-N100).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C Cmotif chemokine; C X C motif chemokine; C-X-C motif chemokine 2; CC motif chemokine; CCmotif chemokine; CINC-3; CXC; CXC motif chemokine; CXCL; Cytokine-induced neutrophil chemoattractant 3; GRO b; gro beta; GRO β; GRObeta; GROβ; Macrophage inflammatory protein 2; MIP 2 a; MIP 2 alpha; MIP 2 α; MIP2; MIP2 a; MIP2 α; small inducible cytokine subfamily, member 2
Gene Aliases: CINC-2a; Cinc3; Cxcl2; Gro2; GROb; Mgsa-b; MIP-2; MIP-2a; Mip2; Scyb; Scyb2
UniProt ID: (Mouse) P10889, (Rat) P30348
Entrez Gene ID: (Mouse) 20310, (Rat) 114105
response to molecule of bacterial origin
positive regulation of leukocyte chemotaxis
chemotaxis
inflammatory response
immune response
G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
neutrophil chemotaxis
leukocyte chemotaxis
response to lipopolysaccharide
regulation of cell proliferation
cell chemotaxis
chemokine-mediated signaling pathway
neuron death
response to amphetamine
response to heat
response to gamma radiation
response to estradiol
wound healing
response to glucocorticoid
cellular response to lipopolysaccharide
cellular response to interleukin-1
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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