|Western Blot (WB)||1-3 µg/ml|
|Tested Species reactivity||Human, Mouse, Non-human primate, Rabbit|
|Host / Isotype||Rabbit / IgG|
|Immunogen||synthetic peptide FLARHRVTSYTS, corresponding to amino acids 330-341 of Human CXCR1.|
|Storage buffer||PBS with 0.2% gelatin|
|Contains||0.05% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
PA1-29466 detects CXCR1 from mouse, human samples. It is also expected to react with chimpanzee, gorilla, and rabbit due to sequence homology.
PA1-29466 has been successfully used in Western blot applications. Predicted molecular weight: 42 kDa.
The PA1-29466 immunogen is: Synthetic peptide: FLARHRVTSYTS, corresponding to amino acids 330-341 of Human CXCR1.
Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze-thaw cycles.
The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C-C; C-C-CKR-1; C-X-C chemokine receptor type 1; CD128; CD181; CDw128a; chemokine (C-X-C motif) receptor 1; CKR-1; CMKAR1; CXC chemokine receptor 1; CXC-R1; CXCR-1; High affinity interleukin-8 receptor A; IL-8 receptor; IL-8 Receptor alpha; IL-8 receptor type 1; IL-8R A; IL-RA; IL8R1; IL8RA; IL8RBA; interleukin 8 receptor alpha; interleukin 8 receptor, alpha; interleukin-8 receptor type 1; interleukin-8 receptor type A
Gene Aliases: C-C; C-C-CKR-1; CD128; CD181; CDw128a; CKR-1; CMKAR1; CXCR1; IL8R1; IL8RA; IL8RBA
Molecular Function: G-protein coupled receptor cell adhesion molecule cytokine receptor defense/immunity protein hydrolase immunoglobulin receptor superfamily immunoglobulin superfamily cell adhesion molecule phosphatase protein phosphatase receptor
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