|Tested species reactivity||Human, Mouse, Non-human primate, Rabbit|
|Host / Isotype||Rabbit / IgG|
|Immunogen||synthetic peptide FLARHRVTSYTS, corresponding to amino acids 330-341 of Human CXCR1.|
|Storage buffer||PBS with 0.2% gelatin|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1-3 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-29466 detects CXCR1 from mouse, human samples. It is also expected to react with chimpanzee, gorilla, and rabbit due to sequence homology.
PA1-29466 has been successfully used in Western blot applications. Predicted molecular weight: 42 kDa.
The PA1-29466 immunogen is: Synthetic peptide: FLARHRVTSYTS, corresponding to amino acids 330-341 of Human CXCR1.
Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze-thaw cycles.
The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.