|Western Blot (WB)||1:1000|
|Tested Species reactivity||Mouse|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide corresponding to residues Y S E E V G S G D Y D S N K E P C F R D E N V H F N R of mouse.|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.01M potassium phosphate, pH 7.2, with 0.14M NaCl, 1mg/ml BSA|
|Contains||0.1% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA1-21625 detects CXCR4 in mouse samples.
PA1-21625 has been successfully used in ELISA, immunohistochemistry and Western blot procedures.
The PA1-21625 immunogen is a synthetic peptide corresponding to residues Y S E E V G S G D Y D S N K E P C F R D E N V H F N R of mouse.
The HIV receptor is composed of two molecules, the CD4 binding receptor and a co-receptor. The human chemokine receptor CxCR4 is one of the co-receptors used by primary isolates of HIV-1. Extracellular domains of human CxCR4 are important for HIV entry into the target cells. Mouse CxCR4 receptor is 91% identical to human CxCR4 and can function as co-receptor when co-expresed with human CD4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C-X-C chemokine receptor type 4; CD184; chemokine (C-X-C) receptor 4; chemokine receptor 4; CXC Chemokine Receptor 4; CXC-R4; CXCR-4; Fusin; HUMSTR; LESTR; Leukocyte-derived seven transmembrane domain receptor; leukocyte-expressed seven-transmembrane-domain; PB-CKR; Pre-B-cell-derived chemokine receptor; SDF-1 receptor; Stromal cell-derived factor 1 receptor
Gene Aliases: b2b220Clo; CD184; Cmkar4; Cxcr4; LESTR; PB-CKR; PBSF/SDF-1; Sdf1r
UniProt ID: (Mouse) P70658
Entrez Gene ID: (Mouse) 12767
Molecular Function: cell adhesion molecule cytokine receptor defense/immunity protein hydrolase immunoglobulin receptor superfamily immunoglobulin superfamily cell adhesion molecule phosphatase protein phosphatase receptor
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