The synthetic peptide sequence is 507-521aa, ISFTFWPFNQEATQQ
Add 0.2 mL of distilled water, will yield a concentration of 500 µg/mL.
CYP11A1, also known as cytochrome P450C11A1, cytochrome P450scc and cytochrome P450, subfamily XIA, is an enzyme that catalyzes the first step of steroid biosynthesis under the modulation of cAMP signal. CYP11A1 in steroidogenic cells converts cholesterol to pregnenolone, which is determined by hormonal control of cholesterol availability. Expression of the CYP11A1 gene is controlled by the transcription factor SF-1, and the upstream SF-1 binding site in the CYP11A1 gene is required for hormonal stimulation. c-Jun and SF-1 may act synergistically to activate CYP11A1 gene expression. Both Forskolin and 8-Br-cAMPS elevate CYP11A1 mRNA levels in the interstitial cell monolayer, which has a fully functional adenylate cyclase.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cholesterol 20-22 desmolase; Cholesterol desmolase; cholesterol monooxygenase (side-chain cleaving); Cholesterol side-chain cleavage enzyme; Cholesterol side-chain cleavage enzyme, mitochondrial; CYP11A; CYP11A1; CYPXIA1; Cytochrome P450 11A1; cytochrome P450 family 11 subfamily A polypeptide 1; Cytochrome P450(scc); cytochrome P450, family 11, subfamily A, polypeptide 1; cytochrome P450, subfamily XIA (cholesterol side chain cleavage); cytochrome P450C11A1; mitochondrial; steroid 20-22-lyase
Gene Aliases: CYP11A; CYP11A1; CYPXIA1; P450SCC
UniProt ID: (Human) P05108
Entrez Gene ID: (Human) 1583