|Western Blot (WB)||0.1-0.3 ug/ml|
|Tested Species reactivity||Human, Rat|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (RKYDIQATDN) corresponding to the internal amino acids of CYP24A1|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 1,25-@dihydroxyvitamin D3 24-hydroxylase; 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial; 24-OHase; 24R-Ohase; 25-hydroxyvitamin D3 24-hydroxylase; CP24; CYP24; CYP24A1; Cytochrom P450 (25-hydroxyvitamin D24-hydroxylase); Cytochrome P450 24A1; cytochrome P450 family 24 subfamily A polypeptide 1; cytochrome P450, family 24, subfamily A, polypeptide 1; cytochrome P450, subfamily 24; cytochrome P450, subfamily XXIV (vitamin D 24-hydroxylase); Cytochrome P450-CC24; exo-mitochondrial protein; MGC126273; MGC126274; P450-CC24; vitamin D 24-hydroxylase; vitamin D(3) 24-hydroxylase
Gene Aliases: 25-hydroxyvitaminD324-hydroxylase; CP24; CYP24; CYP24A1; HCAI; HCINF1; P450-CC24; VITD12
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.