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Invitrogen
CYP26B1 Polyclonal Antibody
Product Details
PA5-15214
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:1,000 | View 1 publication 1 publication |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:10-1:50 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Published species |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
KLH conjugated synthetic peptide between 398-430 amino acids from the C-terminal region of human CYP26B1 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
2 mg/mL |
Purification |
Size-exclusion - Dialysis, Ammonium sulfate precipitation |
Storage buffer |
PBS |
Contains |
0.09% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2292617 |
Product Specific Information
This antibody is predicted to react with mouse and rat based on sequence homology.
Target Information
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and the synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene is involved in the specific inactivation of all-trans-retinoic acid to hydroxylated forms, such as 4-oxo-, 4-OH-, and 18-OH-all-trans-retinoic acid.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Cytochrome P450 26A2; Cytochrome P450 26B1; cytochrome P450 family 26 subfamily A member 1; Cytochrome P450 retinoic acid-inactivating 2; cytochrome P450 retinoid metabolizing protein; cytochrome P450, family 26, subfamily B, polypeptide 1; cytochrome P450, subfamily XXVIB, polypeptide 1; Cytochrome P450RAI-2; P450 26A2; Retinoic acid-metabolizing cytochrome
Gene Aliases: CYP26A2; CYP26B1; P450RAI-2; P450RAI2; RHFCA
UniProt ID: (Human) Q9NR63
Entrez Gene ID: (Human) 56603
Molecular Function:
oxygenase
cell fate determination
establishment of T cell polarity
vitamin metabolic process
xenobiotic metabolic process
inflammatory response
male meiosis
spermatogenesis
proximal/distal pattern formation
positive regulation of gene expression
embryonic limb morphogenesis
retinoic acid catabolic process
tongue morphogenesis
regulation of T cell differentiation
retinoic acid receptor signaling pathway
negative regulation of retinoic acid receptor signaling pathway
oxidation-reduction process
bone morphogenesis
establishment of skin barrier
cornification
cellular response to retinoic acid
positive regulation of tongue muscle cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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