PA5-28159 targets Cytochrome P450 26B in WB applications and shows reactivity with Human samples.
The PA5-28159 immunogen is recombinant fragment corresponding to a region within amino acids 160 and 426 of Human Cytochrome P450 26B.
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This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and the synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene is involved in the specific inactivation of all-trans-retinoic acid to hydroxylated forms, such as 4-oxo-, 4-OH-, and 18-OH-all-trans-retinoic acid.
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Protein Aliases: CYP26A2; Cytochrome P450 26A2; Cytochrome P450 26B1; cytochrome P450 CYP26B1 variant 2; cytochrome P450 family 26 subfamily A member 1; Cytochrome P450 retinoic acid-inactivating 2; cytochrome P450 retinoid metabolizing protein; cytochrome P450, family 26, subfamily B, polypeptide 1; cytochrome P450, subfamily XXVIB, polypeptide 1; Cytochrome P450RAI-2; P450RAI-2; Retinoic acid-metabolizing cytochrome
Gene Aliases: CYP26A2; CYP26B1; P450RAI-2; P450RAI2; RHFCA
UniProt ID: (Human) Q9NR63
Entrez Gene ID: (Human) 56603