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Product Details
H00001580-D01P
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CYP4B1 (AAH17758.1, 1 a.a. approximately 512 a.a) full-length human protein.
Conjugate
Unconjugated
Form
Liquid
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MVPSFLSLSF SSLGLWASGL ILVLGFLKLI HLLLRRQTLA KAMDKFPGPP THWLFGHALE IQETGSLDKV VSWAHQFPYA HPLWFGQFIG FLNIYEPDYA KAVYSRGDPK APDVYDFFLQ WIGRGLLVLE GPKWLQHRKL LTPGFHYDVL KPYVAVFTES TRIMLDKWEE KAREGKSFDI FCDVGHMALN TLMKCTFGRG DTGLGHSRDS SYYLAVSDLT LLMQQRLVSF QYHNDFIYWL TPHGRRFLRA CQVAHDHTDQ VIRERKAALQ DEKVRKKIQN RRHLDFLDIL LGARDEDDIK LSDADLRAEV DTFMFEGHDT TTSGISWFLY CMALYPEHQH RCREEVREIL GDQDFFQWDD LGKMTYLTMC IKESFRLYPP VPQVYRQLSK PVTFVDGRSL PAGSLISMHI YALHRNSAVW PDPEVFDSLR FSTENASKRH PFAFMPFSAG PRNCIGQQFA MSEMKVVTAM CLLRFEFSLD PSRLPIKMPQ LVLRSKNGFH LHLKPLGPGS GK
Target Information
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens; however, the specific function of the human protein has not been determined. Two transcript variants encoding slightly different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CYPIVB1; Cytochrome P450 4B1; cytochrome P450, family 4, subfamily B, polypeptide 1; cytochrome P450, subfamily IV B, polypeptide 1; cytochrome P450, subfamily IVB, polypeptide 1; Cytochrome P450-HP; microsomal monooxygenase
Gene Aliases: CYP4B1; CYPIVB1; P-450HP
UniProt ID: (Human) P13584, (Mouse) Q64462
Entrez Gene ID: (Human) 1580, (Mouse) 13120
iron ion binding
drug binding
toxic substance binding
fluorene oxygenase activity
oxygen binding
heme binding
aromatase activity
monooxygenase activity
oxidoreductase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
metal ion binding
oxygenase
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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