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Proteintech
CYP4F11 Polyclonal Antibody, CoraLite® Plus 488
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
CL488-12286
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CYP4F11 fusion protein Ag2906
Conjugate
CoraLite® Plus 488
CoraLite® Plus 488
CoraLite® Plus 488
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: HDKWQRLAS EGSARLDMFE HISLMTLDSL QKCVFSFESN CQEKPSEYIA AILELSAFVE KRNQQILLHT DFLYYLTPDG QRFRRACHLV HDFTDAVIQE RRRTLPTQGI DDFLKNKAKS KTLDFIDVLL LSKDEDGKEL SDEDIRAEAD TFMFEGHDTT ASGLSWVLYH LAKHPEYQEQ CRQEVQELLK DREPIEIEWD DLAQLPFLTM CIKESLRLHP PVPVISRCCT QDFVLPDGRV IPKGIVCLIN IIGIHYNPTV WPDPEVYDPF RFNQENIKER SPLAFIPFSA GPRNCIGQAF AMAEMKVVLA LTLLHFRILP THTEPRRKPE LILRAEGGLW LRVEPLGANS Q
Target Information
The cytochrome P450 proteins (CYPs) are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. P450 enzymes are classified into subfamilies based on their sequence similarities. CYP4F11 is an isoform of the cytochrome P450 4F protein and is expressed mainly in human liver, followed by kidney, heart, and skeletal muscle. CYP4F11 contains 524 amino acid residues that share 80.0, 82.3 and 79.2% identity to CYP4F2, CYP4F3, and CYP4F8 amino acid sequences, respectively. CYP4F11 has catalytic properties towards endogenous eicosanoids as well as some clinically relevant drugs, and is able to metabolize large molecules such as erythromycin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3-hydroxy fatty acids omega-hydroxylase CYP4F11; cytochrome P450, family 4, subfamily F, polypeptide 11; cytochrome P450, subfamily IVF, polypeptide 11; docosahexaenoic acid omega-hydroxylase; long-chain fatty acid omega-monooxygenase; P450; phylloquinone omega-hydroxylase CYP4F11; unnamed protein product
Gene Aliases: CYPIVF11
UniProt ID: (Human) Q9HBI6
Entrez Gene ID: (Human) 57834
monooxygenase activity
fatty acid binding
iron ion binding
protein binding
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
heme binding
arachidonic acid omega-hydroxylase activity
long-chain fatty acid omega-hydroxylase activity
medium-chain fatty acid omega-hydroxylase activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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