This antibody is predicted to react with mouse and rat based on sequence homology.
Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature. A suggested positive control is thyroid or medullary carcinoma.
Calcitonin is a peptide hormone synthesized by the parafollicular cells of the thyroid. It causes a rapid, but short lived, reduction in serum calcium and phosphate by promoting the incorporation of those ions in the bones. This effect is opposite to that of parathyroid hormone.
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Protein Aliases: Alpha CGRP; Alpha-type CGRP; CALC1; CALCA; Calcitonin; calcitonin 1; Calcitonin carboxyl-terminal peptide; Calcitonin gene-related peptide 1; Calcitonin gene-related peptide I; calcitonin-related polypeptide alpha; calcitonin/calcitonin-related polypeptide, alpha; CCP; CGRP-I; CT; Katacalcin; KC; PDN-21
Gene Aliases: CALC1; CALCA; CGRP; CGRP-I; CGRP1; CT; KC; PCT
UniProt ID: (Human) P06881
Entrez Gene ID: (Human) 796