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Calcium Sensing Receptor Polyclonal Antibody

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Calcium Sensing Receptor Polyclonal Antibody

Product Details

CASR-101AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
-

Immunohistochemistry (IHC)

1:50-1:250
-

ELISA (ELISA)

1:10,000
-

Immunoprecipitation (IP)

1:50-1:250
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to amino acids 47-69 on human CASR gene. Sequence:KDQDLKSRPESVECIRYNFRGFR
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5-1.5 mg/mL

Purification

Affinity chromatography

Storage buffer

proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Senses changes in the extracellular concentration of calcium ions. The activity of this receptor is mediated by a G- protein that activates a phosphatidylinositol-calcium second messenger system.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Ca sensing receptor; calcium receptor|CaR; Calcium-sensing receptor (hypocalciuric hypercalcemia 1 severe neonatal hyperparathyroidism); Calcium-sensing receptor (hypocalciuric hypercalcemia 1, severe neonatal hyperparathyroidism); CaR; CaSR; CaSR antibody; cation sensing receptor; Extracellular calcium-sensing receptor; G protein coupled receptor, family C, group 2, member A; G protein-coupled receptor, family C, group 2, member A; parathyroid Ca(2+)-sensing receptor 1; Parathyroid cell calcium-sensing receptor; Parathyroid cell calcium-sensing receptor 1; PCaR1

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Gene Aliases: CAR; CASR; EIG8; FHH; FIH; GPRC2A; hCasR; HHC; HHC1; HYPOC1; NSHPT; PCAR1

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UniProt ID: (Human) P41180, (Rat) P48442, (Mouse) Q9QY96

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Entrez Gene ID: (Human) 846, (Rat) 24247, (Mouse) 12374

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Function(s)
G-protein coupled receptor activity integrin binding calcium ion binding protein binding amino acid binding protein kinase binding identical protein binding protein homodimerization activity ion channel binding metal ion binding magnesium ion binding drug binding polyamine binding signal transducer activity G-protein coupled receptor
Process(es)
ossification response to ischemia detection of calcium ion cellular calcium ion homeostasis signal transduction G-protein coupled receptor signaling pathway adenylate cyclase-activating G-protein coupled receptor signaling pathway adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway phospholipase C-activating G-protein coupled receptor signaling pathway JNK cascade chemosensory behavior positive regulation of cell proliferation anatomical structure morphogenesis response to metal ion positive regulation of gene expression positive regulation of insulin secretion bile acid secretion cellular response to hepatocyte growth factor stimulus vasodilation positive regulation of vasoconstriction branching morphogenesis of an epithelial tube positive regulation of positive chemotaxis response to calcium ion regulation of calcium ion transport fat pad development positive regulation of ERK1 and ERK2 cascade cellular response to vitamin D cellular response to glucose stimulus cellular response to low-density lipoprotein particle stimulus cellular response to hypoxia response to fibroblast growth factor positive regulation of calcium ion import regulation of presynaptic membrane potential adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway positive regulation of NLRP3 inflammasome complex assembly cellular response to peptide chloride transmembrane transport calcium ion transport apoptotic process response to organic cyclic compound positive regulation of ATPase activity calcium ion import
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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