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Invitrogen
Calcium Sensing Receptor Polyclonal Antibody
Product Details
PA5-85137
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human Calcium Sensing Receptor.
Conjugate
Form
Liquid
Concentration
0.55 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2792284
Product Specific Information
Keep as concentrated solution.
Predicted reactivity: Mouse (93%), Rat (94%), Dog (95%), Cat (95%), Pig (95%), Bovine (95%).
Positive Control: 293T, A431, H1299, HeLa, mouse brain, mouse placenta.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Senses changes in the extracellular concentration of calcium ions. The activity of this receptor is mediated by a G- protein that activates a phosphatidylinositol-calcium second messenger system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ca sensing receptor; calcium-sensing receptor; CaR; CaSR; CaSR antibody; cation sensing receptor; Extracellular calcium-sensing receptor; G protein coupled receptor, family C, group 2, member A; G protein-coupled receptor, family C, group 2, member A; parathyroid Ca(2+)-sensing receptor 1; Parathyroid cell calcium-sensing receptor; Parathyroid cell calcium-sensing receptor 1; PCaR1
Gene Aliases: CAR; CASR; EIG8; FHH; FIH; GPRC2A; HHC; HHC1; HYPOC1; NSHPT; PCAR1
UniProt ID: (Human) P41180, (Mouse) Q9QY96
Entrez Gene ID: (Human) 846, (Mouse) 12374
ossification
detection of calcium ion
cellular calcium ion homeostasis
G-protein coupled receptor signaling pathway
chemosensory behavior
anatomical structure morphogenesis
calcium ion import
calcium ion transport
signal transduction
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
JNK cascade
positive regulation of cell proliferation
positive regulation of gene expression
positive regulation of insulin secretion
positive regulation of ATPase activity
vasodilation
positive regulation of vasoconstriction
branching morphogenesis of an epithelial tube
positive regulation of positive chemotaxis
regulation of calcium ion transport
positive regulation of calcium ion import
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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