Search
Proteintech
Cannabinoid receptor 1 Polyclonal Antibody, CoraLite® Plus 488
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
FIGURE: 1 / 1
Cannabinoid receptor 1 Antibody (CL488-17978) in IHC (PFA)
Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse brain tissue using CoraLite® Plus 488 Cannabinoid receptor 1 antibody (CL488-17978) at dilution of 1:200. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).
Product Details
CL488-17978
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Cannabinoid receptor 1 fusion protein Ag12371
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MKSILDGLA DTTFRTITTD LLYVGSNDIQ YEDIKGDMAS KLGYFPQKFP LTSFRGSPFQ EKMTAGDNPQ LVPADQVNIT EFYNKSLSSF KENEENIQCG ENFMDIECFM VLNPSQQLAI AV
Target Information
This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Brain-type cannabinoid receptor; CANN6; Cannabinoid receptor 1; cannabinoid receptor 1 (brain); CB-R; CB1; CB1 receptor; central cannabinoid receptor; HGNC:2159; N-terminal variant; OTTHUMP00000016839; RP1-23D17.1; striatal cannabinoid receptor type 1 protein; unnamed protein product
Gene Aliases: CANN6; CB-R; CB1; CB1A; CB1K5; CB1R; CNR; CNR1; Skr6; SKR6R
UniProt ID: (Human) P21554, (Mouse) P47746, (Rat) P20272
Entrez Gene ID: (Human) 1268, (Mouse) 12801, (Rat) 25248
signal transduction
G-protein coupled receptor signaling pathway
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
axonal fasciculation
cannabinoid signaling pathway
glucose homeostasis
retrograde trans-synaptic signaling by endocannabinoid
regulation of presynaptic cytosolic calcium ion concentration
positive regulation of acute inflammatory response to antigenic stimulus
aging
learning or memory
memory
positive regulation of neuron projection development
regulation of lipid metabolic process
sensory perception of pain
positive regulation of fever generation
negative regulation of fatty acid beta-oxidation
regulation of synaptic transmission, GABAergic
response to lipopolysaccharide
negative regulation of mast cell activation
negative regulation of dopamine secretion
response to nicotine
response to cocaine
positive regulation of apoptotic process
negative regulation of ion transport
response to morphine
response to ethanol
negative regulation of action potential
negative regulation of blood pressure
positive regulation of blood pressure
regulation of insulin secretion
negative regulation of nitric-oxide synthase activity
regulation of synaptic transmission, glutamatergic
regulation of feeding behavior
regulation of penile erection
spermatogenesis
response to nutrient
maternal process involved in female pregnancy
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support